Which medication will I be prescribed?
Either semaglutide or tirzepatide, depending on health history, other
medications, insurance and how you respond. Neither is universally better, and anyone telling you otherwise is
selling one of them. We compare how they differ, and what the clinical trials actually showed, on our
semaglutide versus tirzepatide page.
What are the side effects?
The most common are gastrointestinal, nausea, diarrhoea, vomiting and constipation, and they are
usually worst in the first weeks after a dose increase. Both medicines also carry a boxed warning about thyroid
tumours observed in rodents.
We publish the full list with the placebo comparison rates straight from the FDA label, which is
the context most articles leave out, on our
GLP-1 side effects page. It covers hair loss, mood, muscle, alcohol and the
long-term warnings.
What results are realistic, and how quickly?
Appetite change is usually noticed within the first weeks. Weight change is slower, measured over months rather
than days, and it varies considerably between people.
The medication works alongside eating and activity changes, not instead of them, and protein intake and
resistance training matter more here than in ordinary dieting, because rapid loss costs lean mass as well as fat.
Anyone promising you a specific number on a specific date is guessing.
What does medical weight loss cost?
It depends on the medication, the dose, and whether any of it is covered by your insurance. We discuss the whole
figure at the consultation rather than publishing a number that will not match your situation. What we will not do is
quote a low headline and add to it later.
What happens if it is not working?
We say so. Sometimes the dose needs adjusting, sometimes the medication is the wrong one for that person, and
sometimes the honest answer is that this is not the right tool at all.
Continuing to bill someone for something that is not helping them is not a service. That is the same standard we
apply to every drip on this site.
This page is education, not medical advice
Semaglutide and tirzepatide are prescription medicines. Whether either is appropriate for you is a clinical
decision made with a prescriber who knows your history. Nothing here should be read as a recommendation to start,
stop or change a medication.